Ahmed Badran
Advisor(s): David Liu
Dissertation Title: Advances in Phage-Assisted Continuous Evolution and Application to Overcoming Bioinsecticide Resistance
Craig Braun
Advisor: Loren Walensky
Dissertation Title: Structural Characterization of BCL-2 Family Interactions Using Photoreactive Stapled Peptides and Mass Spectrometry
Alexandra Cantley
Advisor(s): Jon Clardy
Dissertation Title: Uncovering Bacterial Metabolites Involved in Eukaryotic Development
Jacob Carlson
Advisor: David Liu
Dissertation Title: Continuous Directed Evolution of Enzymes with Novel Substrate Specificity
Alix Chan
Advisor(s): David Liu
Dissertation Title: Harnessing DNA-Encoded Libraries to Discover Bioactive Small Molecules
Grace Chen
Advisor: David Liu
Dissertation Title: The Discovery and Characterization of NAD-Linked RNA
Sixun Chen
Advisor(s): Stuart Schreiber
Dissertation Title: The Study of NSD2 Biochemical and Biological Activity Through Small-Molecule Profiling of Cell Lines
James Cronican
Advisor: David Liu
Dissertation Title: Macromolecule Delivery into Mammalian Cells Using Supercharged Proteins.
Kevin Davis
Advisor(s): David Liu
Dissertation Title: Directed Evolution and Engineering of CRISPR-Associated Nucleases
Samouil Farhi
Advisor: Adam Cohen
Dissertation Title: All-optical Neurophysiology in the 1-photon Regime
Alexander Federation
Advisor(s): James Bradner
Dissertation Title: The Development of Chemical and Computational Tools to Study Transcriptional Regulation in Cancer.
Lisa Freinkman
Advisor: Dan Kahne
Dissertation Title: Assembly and Regulation of the lipopolysacchraide Transporter
Alexander George
Advisor(s): Daniel Kahne
Dissertation Title: Biophysical Studies of the Lpt Pathway
Miriam Ginzberg
Advisor(s): Marc Kirschner
Dissertation Title: Size Control and Uniformity in Animal Cells.
Ilana Goldowitz
Advisor(s): Matthias Marti
Dissertation Title: Plasmodium’s Crossroads: Deciphering the Molecular Pathway That Leads to Malaria Transmission.
Marie Hollenhorst
Advisor: Chris Walsh
Dissertation Title: Biosynthesis and Bioloigcal Activity of the Dapdiamide Antibiotics.
Hai-Tsang "Hubert" Huang
Advisor: Nathanael Gray
Dissertation Title: Exploring Novel Kinase Targets and Novel Pharmacology for Cancer Therapeutics
Cindy Jao
Advisor: Adrian Salic
Dissertation Title: Bioorthogonal Strategies to Image Nucleic Acids, Phospholipids and Sterols in Cells
Liv Johannessen
Advisor: Nathanael Gray
Dissertation Title: Drugging Transcription: Exploring Roles of CDK8 from Cancer to Immunity
Renee Kontik
Advisor: Jon Clardy
Dissertation Title: Isolation and Characterization of Small Molecules Mediating Microbial Symbioses
Nitzan Koppel
Advisor: Emily Balskus
Dissertation Title: Characterization of a Widely Distributed Cardiac Durg-inactivating Enzyme from the Human Gut Bacterium Eggerthella Lenta
Marc Lajoie
Advisor(s): George Church
Dissertation Title: Genome Engineering Technologies to Change the Genetic Code
Pulin Li
Advisor: Len Zon
Dissertation Title: Chemical Genetics of Hematopoietic Stem Cells Transplantation
Alvin Lu
Advisor: Hao Wu
Dissertation Title: Assembly and Regulation of the Inflammasome Governed by a Unified Polymerization Mechanism
Sarah Mahlstedt
Advisor: Chris T. Walsh
Dissertation Title: Novel Routing of Prephanate to Natural Products
Leigh Matano
Advisor: Suzanne Walker
Dissertation Title: Accelerating the Discovery of Antibacterial Compounds to Validate Drug Targets and Probe Cell Physiology of Staphylococcus aureus
Erin May
Advisor(s): Gregory Verdine
Dissertation Title: Lessons from Cyclosporine A: Structural Determinants of Conformation-Switching and Passive Membrane Penetration.
Lynn McGregor
Advisor(s): David Liu
Dissertation Title: Methods for the Identification of Ligand-Target Pairs from Combined Libraries of Targets and Ligands
Michael McKeown
Advisor(s): James Bradner
Dissertation Title: Chemical Probes and the Exploration of Bromodomains in Cancer Biology
Nienke Moret
Email: nienke_moret@hms.harvard.edu
Advisor: Peter Sorger / Christoph Benoist
Year: 2013
Joshua Mosberg
Advisor: George Church
Dissertation Title: Studying and Improving Lambad Red Recombination for Genome Engineering in escherichia coli
Phuong Anh Nguyen
Advisor(s): Timothy Mitchison
Dissertation Title: Spatial Organizing Principles of Cytokinesis Signaling.
Joshiawa Paulk
Advisor(s): Stuart Schreiber
Dissertation Title: Modulators of Cellular and Biochemical PRC2 Activity
Sun Peck
Advisor: David Liu
Dissertation Title: Directed Evolution of Inteins and Protein-protein Interfaces
Steven Poynter
Advisors: Stuart Schreiber & Cigall Kadoch
Dissertation Title: Structural and Functional Insights Into Mammalian SWI/SNF Complex Misassembly in Oncogenesis
Yuan Qiao
Advisor(s): Daniel Kahne & Suzanne Walker
Dissertation Title: Reconstitution of the Final Step of Peptidoglycan Assembly in Staphylococcus aureus
Elizabeth Ransey
Advisor: Piotr Sliz
Dissertation Title: Mechanistic and Functional Studies of RNA Processing Pathway Components
Timothy Roth
Advisor: David Liu
Dissertation Title: Phage Assisted Evolutions for Engineering Biosynthetic Pathways
John SantaMaria
Advisor(s): Suzanne Walker
Dissertation Title: Investigating Synthetic Lethal Interactions with the Wall Teichoic Acid Pathway of Staphylococcus aureus
Marina Santiago
Advisor(s): Suzanne Walker
Dissertation Title: New Genomics Tools and Strategies for Studying Antibiotics and Antibiotic-resistance in Staphylococcus aureus
Katharin Shaw
Advisor(s): James Bradner
Dissertation Title: Chemical Biology Platform to Develop Small Molecule Probes for Bromodomains
Angela She
Advisor: Stephen Haggarty
Dissertation Title: Chemical Neurobiology of Progranulin-Deficient Frontotemporal Dementia
Kenneth Skinner
Advisor(s): Rachelle Gaudet
Dissertation Title: Identifying Druggable Sites in the Pain-sensing TRPA1 Ion Channel
Pia Sorensen
Advisor: Ulrike Eggert
Dissertation Title: Understanding the Mechanism of Cucurbitacin
Alison Stewart
Advisor: Stuart Schreiber
Dissertation Title: Small Molecule Screening of the Hematopoietic Stem Cell Bone Marrow Niche
Laura Stone
Advisor(s): Roy Kishony
Dissertation Title: Drugs That Thwart Antibiotic Resistance
Laura Strittmatter
Advisor(s): Vamsi Mootha
Dissertation Title: Linking Human Genetic Variation to Mitochondrial Metabolism
Justin Tan
Advisor(s): Len Zon
Dissertation Title: The Role of HEXIM1 in the Transcriptional Regulation of Neural Crest Differentiation and Melanoma
Ruiqi Wang
Advisor: Thomas Walz
Dissertation Title: Monolayer Purification and Affinity Grid for Single-Particle Electron Microscopy
Samantha Wellington
Advisor: Deb Hung
Dissertation Title: Identifying New Probes of Essential Targets in Mycobacterium tuberculosis
Jing Zhang
Advisor: Tom Roberts
Dissertation Title: CRKL is an important regulator of PI3K signaling in PTEN-deficient tumors.
